The DEF6 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to DEF6. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The DEF6 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor(GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2(T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling(By similarity)